'
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.6
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 3 tablets
Serving Per Container: 83
Amount Per Serving
%DV
Calcium (as calcium carbonate, calcium gluconate, calcium citrate)
1,000 mg
77%
Magnesium (as magnesium oxide, magnesium gluconate, magnesium citrate)
400 mg
95%
Zinc (as zinc gluconate)
15 mg
136%
Sodium†
15 mg
<1%

Top Medical Research Studies

9
Zinc treatment for angina pectoris
High-dose zinc to terminate angina pectoris: a review and hypothesis for action by ICAM inhibition.
Directly addresses zinc treatment
We delved into an intriguing question: Can high doses of zinc help relieve chest pain caused by angina pectoris? Our research reviewed studies that highlight how zinc may play a role in managing this condition. Angina pectoris often results from arteriosclerosis, where the arteries become narrowed due to cholesterol buildup and other factors.

We discovered that patients with severe atherosclerosis showed promising improvements when treated with high-dose zinc. Specifically, a treatment regimen involved raising serum zinc levels significantly, resulting in symptom relief for many individuals. In one notable case, 12 out of 16 patients experienced measurable benefits, including one patient who also suffered from Raynaud's disease.

Furthermore, our analysis noted that long-term exposure to zinc in the environment correlated with reduced incidence of angina and ischemic events during exercise. Zinc appears to possess antioxidant properties, which may protect against the oxidation of LDL cholesterol, a key player in artery damage. By blocking certain inflammatory factors and promoting better circulation, zinc might enhance heart function and alleviate chest pain.

Based on these findings, we propose that zinc treatment should be considered a fundamental option in both prevention and therapy for atherosclerosis-related chest pain. This could lead to a renewed focus on restoring a healthier cardiac function among those affected by these conditions.
Read More
8
Magnesium supplementation aids chest pain
The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy.
Direct focus on magnesium treatment
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.

After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.

After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.

Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Read More
7
Magnesium treatment ineffective for chest pain
Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room".
Direct assessment of magnesium's effects
We explored the effects of magnesium treatment on individuals experiencing chest pain, particularly considering its role in preventing serious heart conditions. The study carefully evaluated how magnesium might mitigate the discomfort linked to coronary issues, providing a focused observation of its immediate impact on chest pain symptoms.

Throughout the research, we aimed to determine whether magnesium could offer a significant relief to patients. Our findings, however, revealed that while magnesium has various health benefits, it did not show a significant effect on alleviating chest pain in the observed population.

Despite its widely recognized benefits in other contexts, we concluded that magnesium treatment might not be the solution for chest pain relief that many have hoped for. More research is required to better understand how we might effectively treat chest pain in various patients.
Read More

Most Useful Reviews

8.3
Relief from pain
I feel relieved from back pain! After taking this, I am very comfortable.
Read More
8.3
Joint pain relief
After taking this complex, the pain in my legs and joints disappeared, and the condition of my teeth improved. I will continue taking it.
Read More
7.5
Less pain concern
This is a good option for osteoporosis; my pain has become less of a concern. I took D3 at the same time.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.6
9.5
Calcium treatment effective for angina
Case Report: Vasospastic angina presenting as phantom odor perception.
Highlights calcium treatment relevance
We looked at the case of a 69-year-old woman experiencing intermittent shortness of breath and chest pain. Interestingly, she also described a peculiar symptom—a phantom odor sensation that preceded her episodes. During an exercise stress echocardiography, she demonstrated abnormal smell perception alongside transient changes in her heart's electrical activity, which indicated possible cardiac issues.

After conducting invasive coronary angiography, no significant blockages were found in her coronary arteries. This led to a diagnosis of vasospastic angina, a condition that can cause chest pain due to spasms in the coronary arteries rather than physical blockages. To alleviate her symptoms, she was started on calcium channel blocker therapy. Thankfully, this treatment helped in resolving her discomfort.

While the study highlights the role of calcium treatment in managing her symptoms effectively, it's essential to note that this isn't a guaranteed solution for everyone with chest pain. Phantom odors as an indicative symptom of cardiovascular issues are quite rare, suggesting a need for healthcare providers to remain vigilant when patients present with atypical symptoms.
Read More
9.5
Calcium channels alleviate chest pain
Bilateral isolated coronary ostial stenosis in a middle-aged premenopausal woman with vasospastic angina: a case report.
Relevant but contextually limited
We explored the unusual case of a 50-year-old premenopausal woman suffering from vasospastic angina (VSA), a form of chest pain resulting from coronary artery spasms. Our patient's daily chest pain, triggered by light exertion, led to testing that revealed mild-to-moderate isolated coronary ostial stenosis (ICOS) along with multi-vessel spasms.

Interestingly, despite the severity often associated with ICOS, she experienced considerable relief after starting treatment with calcium channel blockers (CCBs). This finding is significant as it shows how CCB therapy can effectively manage VSA symptoms, leading to alleviation of chest pain without the need for surgical intervention for ICOS—even over a stretch of 24 years.

Notably, follow-up imaging after this duration indicated that ICOS had resolved, suggesting a remarkable possibility of improvement. However, we should remember that while the use of CCBs proved beneficial in this instance, the results highlight the ongoing need for research into the efficacy of different treatments for chest pain.
Read More
9.5
Magnesium's unclear role in chest pain
An adolescent with tingling and numbness of hand: gitelman syndrome.
Moderate relevance; combined therapy analyzed
We examined the role of magnesium in treating chest pain, particularly in a case involving a young female with Gitelman syndrome. This patient experienced recurrent chest pain alongside symptoms like tingling and numbness, prompting a thorough investigation into her condition.

Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.

While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
Read More
9
Calcium treatment aids chest pain
Managing heart failure with reduced ejection fraction merged with myocardial infarction with non-obstructive coronary arteries: a case report.
Score suggests significant relevance
We explored how calcium channel blockers (CCBs) can help patients with chest pain, particularly in those who also have heart failure with reduced ejection fraction (HFrEF) and myocardial infarction with non-obstructive coronary arteries (MINOCA).

An 83-year-old woman was admitted with significant shortness of breath and a notable decline in her heart's pumping ability, also accompanied by intermittent chest pain. Although initial tests showed no major blockages in her coronary arteries, a more precise method revealed that she was experiencing severe coronary spasms.

After starting her on dihydropyridine CCBs, we observed a remarkable improvement. Her chest pain gradually went away, and her heart function improved dramatically, as indicated by her higher ejection fraction and lower levels of heart stress markers.

This suggests that CCBs, although not commonly prescribed for HFrEF, can have a useful role in managing chest pain and improving heart function in specific cases. Therefore, we found that tailored treatments and comprehensive diagnostic approaches can lead to better outcomes for patients with similar conditions.
Read More
9
Zinc treatment for angina pectoris
High-dose zinc to terminate angina pectoris: a review and hypothesis for action by ICAM inhibition.
Directly addresses zinc treatment
We delved into an intriguing question: Can high doses of zinc help relieve chest pain caused by angina pectoris? Our research reviewed studies that highlight how zinc may play a role in managing this condition. Angina pectoris often results from arteriosclerosis, where the arteries become narrowed due to cholesterol buildup and other factors.

We discovered that patients with severe atherosclerosis showed promising improvements when treated with high-dose zinc. Specifically, a treatment regimen involved raising serum zinc levels significantly, resulting in symptom relief for many individuals. In one notable case, 12 out of 16 patients experienced measurable benefits, including one patient who also suffered from Raynaud's disease.

Furthermore, our analysis noted that long-term exposure to zinc in the environment correlated with reduced incidence of angina and ischemic events during exercise. Zinc appears to possess antioxidant properties, which may protect against the oxidation of LDL cholesterol, a key player in artery damage. By blocking certain inflammatory factors and promoting better circulation, zinc might enhance heart function and alleviate chest pain.

Based on these findings, we propose that zinc treatment should be considered a fundamental option in both prevention and therapy for atherosclerosis-related chest pain. This could lead to a renewed focus on restoring a healthier cardiac function among those affected by these conditions.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
8.3
Relief from pain
I feel relieved from back pain! After taking this, I am very comfortable.
8.3
Joint pain relief
After taking this complex, the pain in my legs and joints disappeared, and the condition of my teeth improved. I will continue taking it.
7.5
Less pain concern
This is a good option for osteoporosis; my pain has become less of a concern. I took D3 at the same time.
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